Our Goal:
Our goal is to uncover the pivotal role of non-coding RNAs in cardiovascular diseases, including their potential to serve as both therapeutic targets and diagnostic biomarkers. Non-coding RNAs, which do not code for proteins, play essential roles in gene regulation and cellular function. When these molecular orchestrators are dysregulated, they can contribute to a variety of cardiovascular conditions, from heart failure to atherosclerosis. By understanding these processes at the molecular level, we strive to develop innovative therapies and diagnostic tools that can improve patient outcomes.

Areas of Research:

• Access to Multiple Cohorts: We have access to a broad range of cardiovascular cohorts that provide valuable biological samples and clinical data. These resources enable us to explore the molecular landscape of heart failure and other cardiovascular diseases, accelerating the identification of key biomarkers and therapeutic targets.

• Non-Coding RNAs in Cardiovascular Diseases: We investigate the diverse roles of non-coding RNAs, such as microRNAs, long non-coding RNAs, and circular RNAs, in the regulation of cardiovascular health and disease.

• Molecular Mechanisms of Disease Progression: Our research focuses on how non-coding RNAs modulate key cellular processes, including inflammation, fibrosis, and vascular remodeling, which drive the progression of heart disease.

• Therapeutic Target Identification: By identifying specific non-coding RNAs involved in cardiovascular disease, we aim to develop targeted therapies that can modulate their activity and halt or reverse disease progression.

• Cardiovascular Theranostics: We are pioneering the development of diagnostic tools that utilize non-coding RNAs as biomarkers for early detection and monitoring of cardiovascular diseases, enhancing precision medicine and patient care.

Our Impact:
Our work integrates cutting-edge molecular biology techniques with translational research, bridging the gap between basic science and clinical applications. By focusing on non-coding RNAs, we are uncovering new insights into the molecular underpinnings of cardiovascular diseases, with the potential to transform both treatment strategies and diagnostic approaches. Through collaborations, we are working to bring these discoveries to the clinic, developing innovative theranostic solutions that can change the landscape of cardiovascular healthcare.

We invite prospective students, collaborators, and funders to join us in our mission to explore the untapped potential of non-coding RNAs in cardiovascular health.