Publications - Year 2023

1.    Costantino S, Mengozzi A, Velagapudi S, Mohammed SA, Gorica E, Akhmedov A, Mongelli A, Pugliese NR, Masi S, Virdis A, Hülsmeier A, Matter CM, Hornemann T, Melina G, Ruschitzka F, Luscher TF, Paneni F. Treatment with recombinant Sirt1 rewires the cardiac lipidome and rescues diabetes-related metabolic cardiomyopathy. Cardiovasc Diabetol. 2023 Nov 13;22(1):312. doi: 10.1186/s12933-023-02057-2. PMID: 37957697; PMCID: PMC10644415.

2.    Gaul DS, Calatayud N, Pahla J, Bonetti NR, Wang YJ, Weber J, Ambrosini S, Liberale L, Costantino S, Mohammed SA, Kraler S, Van Tits LJ, Pasterk L, Vdovenko D, Akhmedov A, Ruschitzka F, Paneni F, Lüscher TF, Camici GG, Matter CM. Endothelial SIRT6 deficiency promotes arterial thrombosis in mice. J Mol Cell Cardiol. 2023 Jan;174:56-62. doi: 10.1016/j.yjmcc.2022.11.005. Epub 2022 Nov 19. PMID: 36414111.

3.    Renikunta HV, Lazarow K, Gong Y, Shukla PC, Nageswaran V, Giral H, Kratzer A, Opitz L, Engel FB, Haghikia A, Costantino S, Paneni F, von Kries JP, Streckfuss-Bömeke K, Landmesser U, Jakob P. Large-scale microRNA functional high-throughput screening identifies miR-515-3p and miR-519e-3p as inducers of human cardiomyocyte proliferation. iScience. 2023 Apr 8;26(5):106593. doi: 10.1016/j.isci.2023.106593. PMID: 37250320; PMCID: PMC10214393.

4.    Ambrosini S, Montecucco F, Kolijn D, Pedicino D, Akhmedov A, Mohammed SA, Herwig M, Gorica E, Szabó PL, Weber L, Russo G, Vinci R, Matter CM, Liuzzo G, Brown PJ, Rossi FMV, Camici GG, Sciarretta S, Beltrami AP, Crea F, Podesser B, Lüscher TF, Kiss A, Ruschitzka F, Hamdani N, Costantino S, Paneni F. Methylation of the Hippo effector YAP by the methyltransferase SETD7 drives myocardial ischaemic injury: a translational study. Cardiovasc Res. 2023 Jan 18;118(17):3374-3385. doi: 10.1093/cvr/cvac102. PMID: 35709329.

5.    Al-Kindi S, Paneni F, Brook RD, Rajagopalan S. Residual environmental risk in patients with cardiovascular disease: an overlooked paradigm. Eur Heart J. 2023 Nov 21;44(44):4612-4614. doi: 10.1093/eurheartj/ehad412. PMID: 37431798; PMCID: PMC10659939.

6.    Mengozzi A, Costantino S, Mongelli A, Mohammed SA, Gorica E, Delfine V, Masi S, Virdis A, Ruschitzka F, Paneni F. Epigenetic Signatures in Arterial Hypertension: Focus on the Microvasculature. Int J Mol Sci. 2023 Mar 2;24(5):4854. doi: 10.3390/ijms24054854. PMID: 36902291; PMCID: PMC10003673.

7.    Geiger M, Oppi S, Nusser-Stein S, Costantino S, Mohammed SA, Gorica E, Hoogerland JA, Matter CM, Guillaumon AT, Ruschitzka F, Paneni F, Oosterveer MH, Stein S. Genetic deletion of hepatic NCOR1 protects from atherosclerosis by promoting alternative bile acid-metabolism and sterol excretion. Cardiovasc Diabetol. 2023 Jun 22;22(1):144. doi: 10.1186/s12933-023-01865-w. PMID: 37349757; PMCID: PMC10288794.

8.    Chiapperino L, Paneni F. Walk on the wild side: a response to Zaina. Epigenetics Commun. 2023;3(1):3. doi: 10.1186/s43682-023-00019-z. Epub 2023 May 17. PMID: 38799083; PMCID: PMC11116241.

9.    Schütz V, Dougoud S, Bracher K, Arnold M, Schweizer J, Nakas C, Westphal LP, Inauen C, Pokorny T, Duru F, Steffel J, Luft A, Spanaus K, Saguner AM, Katan M. The Role of Electrocardiographic Markers for Predicting Atrial Fibrillation in Patients with Acute Ischemic Stroke: Data from the BIOSIGNAL Cohort Study. J Clin Med. 2023 Oct 29;12(21):6830. doi: 10.3390/jcm12216830. PMID: 37959294; PMCID: PMC10649302.

10. Jurisic S, Medeiros-Domingo A, Berger F, Balmer C, Brunckhorst C, Ruschitzka F, Saguner AM, Duru F. Catecholaminergic Polymorphic Ventricular Tachycardia: Multiple Clinical Presentations of a Genetically Determined Disease. J Clin Med. 2023 Dec 21;13(1):47. doi: 10.3390/jcm13010047. PMID: 38202054; PMCID: PMC10779837.

11. Kovacs B, Mayinger M, Ehrbar S, Fesslmeier D, Ahmadsei M, Sazgary L, Manka R, Alkadhi H, Ruschitzka F, Duru F, Papachristofilou A, Sticherling C, Blamek S, Gołba KS, Guckenberger M, Saguner AM, Andratschke N. Dose escalation for stereotactic arrhythmia radioablation of recurrent ventricular tachyarrhythmia - a phase II clinical trial. Radiat Oncol. 2023 Nov 8;18(1):185. doi: 10.1186/s13014-023-02361-x. PMID: 37941012; PMCID: PMC10634182.

12. Reiner MF, Schmidt D, Frischknecht L, Ruschitzka F, Duru F, Saguner AM. Case report of long-term postural tachycardia syndrome in a patient after messenger RNA coronavirus disease-19 vaccination with mRNA-1273. Eur Heart J Case Rep. 2023 Aug 19;7(8):ytad390. doi: 10.1093/ehjcr/ytad390. PMID: 37650075; PMCID: PMC10464593.

13. Saguner AM, Lunk D, Mohsen M, Knecht S, Akdis D, Costa S, Gasperetti A, Duru F, Rossi VA, Brunckhorst CB. Electroanatomical voltage mapping with contact force sensing for diagnosis of arrhythmogenic right ventricular cardiomyopathy. Int J Cardiol. 2023 Dec 1;392:131289. doi: 10.1016/j.ijcard.2023.131289. Epub 2023 Aug 22. PMID: 37619879.

14. Guan F, Saguner AM, Breitenstein A, Wang M, Molitor N, Brunckhorst C, Wolber T, Duru F. The effect of first step right atrial mapping (FRAM) on ablation duration and fluoroscopy exposure during cavotricuspid isthmus ablation of atrial flutter. Front Cardiovasc Med. 2023 Jun 6;10:1205966. doi: 10.3389/fcvm.2023.1205966. PMID: 37346289; PMCID: PMC10279846.

15. Mongelli A, Mengozzi A, Geiger M, Gorica E, Mohammed SA, Paneni F, Ruschitzka F, Costantino S. Mitochondrial epigenetics in aging and cardiovascular diseases. Front Cardiovasc Med. 2023 Jul 13;10:1204483. doi: 10.3389/fcvm.2023.1204483. PMID: 37522089; PMCID: PMC10382027.

16. Chioncel O, Adamo M, Nikolaou M, Parissis J, Mebazaa A, Yilmaz MB, Hassager C, Moura B, Bauersachs J, Harjola VP, Antohi EL, Ben-Gal T, Collins SP, Iliescu VA, Abdelhamid M, Čelutkienė J, Adamopoulos S, Lund LH, Cicoira M, Masip J, Skouri H, Gustafsson F, Rakisheva A, Ahrens I, Mortara A, Janowska EA, Almaghraby A, Damman K, Miro O, Huber K, Ristic A, Hill L, Mullens W, Chieffo A, Bartunek J, Paolisso P, Bayes-Genis A, Anker SD, Price S, Filippatos G, Ruschitzka F, Seferovic P, Vidal-Perez R, Vahanian A, Metra M, McDonagh TA, Barbato E, Coats AJS, Rosano GMC. Acute heart failure and valvular heart disease: A scientific statement of the Heart Failure Association, the Association for Acute CardioVascular Care and the European Association of Percutaneous Cardiovascular Interventions of the European Society of Cardiology. Eur J Heart Fail. 2023 Jul;25(7):1025-1048. doi: 10.1002/ejhf.2918. Epub 2023 Jun 13. PMID: 37312239.

17. Ammirati E, Lupi L, Palazzini M, Ciabatti M, Rossi VA, Gentile P, Uribarri A, Vecchio CR, Nassiacos D, Cereda A, Conca C, Tumminello G, Piriou N, Lelarge C, Pedrotti P, Stucchi M, Peretto G, Galasso M, Huang F, Ianni U, Procopio A, Saponara G, Cimaglia P, Tomasoni D, Moroni F, Turco A, Sala S, Di Tano G, Bollano E, Moro C, Abbate A, Della Bona R, Porto I, Carugo S, Campodonico J, Pontone G, Grosu A, Bolognese L, Salamanca J, Diez-Villanueva P, Ozieranski K, Tyminska A, Sardo Infirri L, Bromage D, Cannatà A, Hong KN, Adamo M, Quattrocchi G, Foà A, Potena L, Garascia A, Giannattasio C, Adler ED, Sinagra G, Ruschitzka F, Camici PG, Metra M, Pieroni M. Outcome and Morphofunctional Changes on Cardiac Magnetic Resonance in Patients With Acute Myocarditis Following mRNA COVID-19 Vaccination. Circ Heart Fail. 2023 Jun;16(6):e010315. doi: 10.1161/CIRCHEARTFAILURE.122.010315. Epub 2023 May 15. PMID: 37183708.

18. Perone F, Bernardi M, Redheuil A, Mafrica D, Conte E, Spadafora L, Ecarnot F, Tokgozoglu L, Santos-Gallego CG, Kaiser SE, Fogacci F, Sabouret A, Bhatt DL, Paneni F, Banach M, Santos R, Biondi Zoccai G, Ray KK, Sabouret P. Role of Cardiovascular Imaging in Risk Assessment: Recent Advances, Gaps in Evidence, and Future Directions. J Clin Med. 2023 Aug 26;12(17):5563. doi: 10.3390/jcm12175563. PMID: 37685628; PMCID: PMC10487991.

19. Banach M, Penson PE, Farnier M, Fras Z, Latkovskis G, Laufs U, Paneni F, Parini P, Pirro M, Reiner Ž, Vrablik M, Escobar C. Bempedoic acid in the management of lipid disorders and cardiovascular risk. 2023 position paper of the International Lipid Expert Panel (ILEP). Prog Cardiovasc Dis. 2023 Jul-Aug;79:2-11. doi: 10.1016/j.pcad.2023.03.001. Epub 2023 Mar 7. PMID: 36889490.

20. Chiapperino L, Paneni F. In medio stat virtus? A reply to Dupras. Epigenetics Commun. 2023;3(1):5. doi: 10.1186/s43682-023-00017-1. Epub 2023 May 18. PMID: 38799084; PMCID: PMC11116170.

21. Li J, Charpentier F, Maguy A. Long QT: Time to cut cholesterol? Int J Cardiol Heart Vasc. 2023 Jan 29;45:101179. doi: 10.1016/j.ijcha.2023.101179. PMID: 36793332; PMCID: PMC9922803.

22. Maguy A, Mahendran Y, Tardif JC, Busseuil D, Li J. Autoimmune Atrial Fibrillation. Circulation. 2023 Aug 8;148(6):487-498. doi: 10.1161/CIRCULATIONAHA.122.062776. Epub 2023 Jul 4. PMID: 37401487; PMCID: PMC10399945.

23. Kis L, Li J. Proof of concept for monoclonal antibody therapy in a cellular model of acquired long QT syndrome type 3. Am J Physiol Heart Circ Physiol. 2024 Jan 1;326(1):H89-H95. doi: 10.1152/ajpheart.00628.2023. Epub 2023 Nov 10. PMID: 37947435; PMCID: PMC11213474.

24. Vinci R, d'Aiello A, Costantino S, Capocchiano ND, Matamalas JT, Pedicino D. Editorial: Artificial intelligence applied to coronary artery diseases: from pathophysiology to precision medicine. Front Cardiovasc Med. 2023 Aug 9;10:1247620. doi: 10.3389/fcvm.2023.1247620. PMID: 37621561; PMCID: PMC10446472.

25. Luciani M, Montalbano M, Troncone L, Bacchin C, Uchida K, Daniele G, Jacobs Wolf B, Butler HM, Kiel J, Berto S, Gensemer C, Moore K, Morningstar J, Diteepeng T, Albayram O, Abisambra JF, Norris RA, Di Salvo TG, Prosser B, Kayed R, Del Monte F. Big tau aggregation disrupts microtubule tyrosination and causes myocardial diastolic dysfunction: from discovery to therapy. Eur Heart J. 2023 May 1;44(17):1560-1570. doi: 10.1093/eurheartj/ehad205. Erratum in: Eur Heart J. 2023 Sep 14;44(35):3335. doi: 10.1093/eurheartj/ehad439. PMID: 37122097; PMCID: PMC10324644.

26. Allemann MS, Lee P, Beer JH, Saeedi Saravi SS. Targeting the redox system for cardiovascular regeneration in aging. Aging Cell. 2023 Dec;22(12):e14020. doi: 10.1111/acel.14020. Epub 2023 Nov 13. PMID: 37957823; PMCID: PMC10726899.

27. Bonetti NR, Jouppila AS, Saeedi Saravi SS, Cooley BC, Pasterk L, Liberale LL, Gobbato S, Lüscher TF, Camici GG, Lassila RP, Beer JH. Intravenously administered APAC, a dual AntiPlatelet AntiCoagulant, targets arterial injury site to inhibit platelet thrombus formation and tissue factor activity in mice. Thromb Res. 2023 Aug;228:163-171. doi: 10.1016/j.thromres.2023.04.010. Epub 2023 Apr 25. PMID: 37331119.

28. Saeedi Saravi SS, Bonetti NR, Vukolic A, Vdovenko D, Lee P, Liberale L, Basso C, Rizzo S, Akhmedov A, Lüscher TF, Camici GG, Beer JH. Long-term dietary n3 fatty acid prevents aging-related cardiac diastolic and vascular dysfunction. Vascul Pharmacol. 2023 Jun;150:107175. doi: 10.1016/j.vph.2023.107175. Epub 2023 Apr 25. PMID: 37105373.

29. Stähli BE, Varbella F, Linke A, Schwarz B, Felix SB, Seiffert M, Kesterke R, Nordbeck P, Witzenbichler B, Lang IM, Kessler M, Valina C, Dibra A, Rohla M, Moccetti M, Vercellino M, Gaede L, Bott-Flügel L, Jakob P, Stehli J, Candreva A, Templin C, Schindler M, Wischnewsky M, Zanda G, Quadri G, Mangner N, Toma A, Magnani G, Clemmensen P, Lüscher TF, Münzel T, Schulze PC, Laugwitz KL, Rottbauer W, Huber K, Neumann FJ, Schneider S, Weidinger F, Achenbach S, Richardt G, Kastrati A, Ford I, Maier W, Ruschitzka F; MULTISTARS AMI Investigators. Timing of Complete Revascularization with Multivessel PCI for Myocardial Infarction. N Engl J Med. 2023 Oct 12;389(15):1368-1379. doi: 10.1056/NEJMoa2307823. Epub 2023 Aug 27. PMID: 37634190.

30. Vrotniakaite-Bajerciene K, Rütsche S, Calzavarini S, Quarroz C, Stalder O, Mean M, Righini M, Staub D, Beer JH, Frauchiger B, Osterwalder J, Kucher N, Matter CM, Husmann M, Banyai M, Aschwanden M, Mazzolai L, Hugli O, Rodondi N, Aujesky D, Angelillo-Scherrer A. Thrombin Generation Is Associated with Venous Thromboembolism Recurrence, but Not with Major Bleeding and Death in the Elderly: A Prospective Multicenter Cohort Study. J Clin Med. 2023 Sep 19;12(18):6050. doi: 10.3390/jcm12186050. PMID: 37762997; PMCID: PMC10531633.

31. Mengozzi A, de Ciuceis C, Dell'oro R, Georgiopoulos G, Lazaridis A, Nosalski R, Pavlidis G, Tual-Chalot S, Agabiti-Rosei C, Anyfanti P, Camargo LL, Dąbrowska E, Quarti-Trevano F, Hellmann M, Masi S, Mavraganis G, Montezano AC, Rios FJ, Winklewski PJ, Wolf J, Costantino S, Gkaliagkousi E, Grassi G, Guzik TJ, Ikonomidis I, Narkiewicz K, Paneni F, Rizzoni D, Stamatelopoulos K, Stellos K, Taddei S, Touyz RM, Triantafyllou A, Virdis A. The importance of microvascular inflammation in ageing and age-related diseases: a position paper from the ESH working group on small arteries, section of microvascular inflammation. J Hypertens. 2023 Oct 1;41(10):1521-1543. doi: 10.1097/HJH.0000000000003503. Epub 2023 Jul 20. PMID: 37382158.

32. De Biase N, Mazzola M, Del Punta L, Di Fiore V, De Carlo M, Giannini C, Costa G, Paneni F, Mengozzi A, Nesti L, Gargani L, Masi S, Pugliese NR. Haemodynamic and metabolic phenotyping of patients with aortic stenosis and preserved ejection fraction: A specific phenotype of heart failure with preserved ejection fraction? Eur J Heart Fail. 2023 Nov;25(11):1947-1958. doi: 10.1002/ejhf.3018. Epub 2023 Sep 14. PMID: 37655676.

33. Lapikova-Bryhinska T, Ministrini S, Puspitasari YM, Kraler S, Mohamed SA, Costantino S, Paneni F, Khetsuriani M, Bengs S, Liberale L, Montecucco F, Krampla W, Riederer P, Hinterberger M, Fischer P, Lüscher TF, Grünblatt E, Akhmedov A, Camici GG. Long non-coding RNAs H19 and NKILA are associated with the risk of death and lacunar stroke in the elderly population. Eur J Intern Med. 2024 May;123:94-101. doi: 10.1016/j.ejim.2023.11.013. Epub 2023 Nov 18. PMID: 37981527.

34. Ntinopoulos V, Haeussler A, Odavic D, Papadopoulos N, Rings L, Dushaj S, Rodriguez Cetina Biefer H, Dzemali O. Conversion from off-pump to on-pump coronary artery bypass grafting: impact of surgeon and anaesthetist experience. Interdiscip Cardiovasc Thorac Surg. 2023 Dec 5;37(6):ivad205. doi: 10.1093/icvts/ivad205. PMID: 38123498; PMCID: PMC10751234.

35. Stähli BE, Scharl M, Matter CM. A roadmap for gut microbiome-derived aromatic amino acids for improved cardiovascular risk stratification. Eur Heart J. 2023 Aug 22;44(32):3097-3099. doi: 10.1093/eurheartj/ehad367. PMID: 37366150.

36. Matter MA, Candreva A, Stähli BE, Heg D, Klingenberg R, Räber L, Windecker S, Rodondi N, Nanchen D, Mach F, Gencer B, Ruschitzka F, Matter CM, Templin C. Higher 1-year mortality on rest days in patients with acute coronary syndromes and decompensated heart failure-A SPUM-ACS sub-study. Catheter Cardiovasc Interv. 2024 Feb;103(2):286-294. doi: 10.1002/ccd.30938. Epub 2023 Dec 25. PMID: 38145467.

37. Rossi VA, Laptseva N, Nebunu D, Haider T, Nägele MP, Ruschitzka F, Sudano I, Flammer AJ. Impaired retinal micro-vascular function in patients with atrial fibrillation. Int J Cardiol. 2024 Mar 1;398:131592. doi: 10.1016/j.ijcard.2023.131592. Epub 2023 Nov 17. PMID: 37979794.

38. Lund LH, Crespo-Leiro MG, Laroche C, Garcia-Pinilla JM, Bennis A, Vataman EB, Polovina M, Radovanovic S, Apostolovic SR, Ašanin M, Gackowski A, Kaplon-Cieslicka A, Cabac-Pogorevici I, Anker SD, Chioncel O, Coats AJS, Filippatos G, Lainscak M, Mcdonagh T, Mebazaa A, Metra M, Piepoli M, Rosano GM, Ruschitzka F, Savarese G, Seferović PM, Iung B, Popescu BA, Maggioni AP; ESC EORP HF III National Leaders and Investigators. Rationale and design of the ESC Heart Failure III Registry - Implementation and discovery. Eur J Heart Fail. 2023 Dec;25(12):2316-2330. doi: 10.1002/ejhf.3087. Epub 2023 Nov 29. PMID: 37990135.

39. Rossi VA, Nebunu D, Haider T, Laptseva N, Naegele MP, Ruschitzka F, Sudano I, Flammer AJ. Diverging role of epicardial adipose tissue across the entire heart failure spectrum. ESC Heart Fail. 2023 Dec;10(6):3419-3429. doi: 10.1002/ehf2.14483. Epub 2023 Sep 11. PMID: 37697706; PMCID: PMC10682858.